The Hong Kong University of Science and Technology (HKUST) is a world-renowned international research university. With a strong track record of cultivating high end talents and nurturing future leaders for academia and industry, HKUST is well positioned to craft an innovative approach to cross-disciplinary education and research in the Guangzhou (GZ) campus (https://hkust-gz.edu.cn/). The Ministry of Education of People's Republic of China officially approved the establishment of HKUST (GZ) in June 2022. Located in Qingsheng Hub Cluster, Nansha, Guangzhou, HKUST (GZ) will open its door on September 1, 2022. The intended areas of focus in the GZ Campus will be thematic and cross-disciplinary in nature, synergistic with HKUST without overlapping academic degrees or structures. 4 Academic Hubs (equivalent to schools) with 16 Thrust Areas (equivalent to departments) are now in place.